Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection

The mechanisms that mediate durable protection against Staphylococcus aureus skin reinfections are unclear, as recurrences are common despite high antibody titers and memory T cells. Here, we developed a mouse model of S. aureus skin reinfection to investigate protective memory responses. In contras...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Dillen, Carly A., Pinsker, Bret L., Marusina, Alina I., Merleev, Alexander A., Farber, Orly N., Liu, Haiyun, Archer, Nathan K., Lee, Da B., Wang, Yu, Ortines, Roger V., Lee, Steven K., Marchitto, Mark C., Cai, Shuting S., Ashbaugh, Alyssa G., May, Larissa S., Holland, Steven M., Freeman, Alexandra F., Miller, Loren G., Yeaman, Michael R., Simon, Scott I., Milner, Joshua D., Maverakis, Emanual, Miller, Lloyd S.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824877/
https://ncbi.nlm.nih.gov/pubmed/29400698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96481
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