Factor XII and uPAR upregulate neutrophil functions to influence wound healing

Coagulation factor XII (FXII) deficiency is associated with decreased neutrophil migration, but the mechanisms remain uncharacterized. Here, we examine how FXII contributes to the inflammatory response. In 2 models of sterile inflammation, FXII-deficient mice (F12(–/–)) had fewer neutrophils recruit...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Stavrou, Evi X., Fang, Chao, Bane, Kara L., Long, Andy T., Naudin, Clément, Kucukal, Erdem, Gandhi, Agharnan, Brett-Morris, Adina, Mumaw, Michele M., Izadmehr, Sudeh, Merkulova, Alona, Reynolds, Cindy C., Alhalabi, Omar, Nayak, Lalitha, Yu, Wen-Mei, Qu, Cheng-Kui, Meyerson, Howard J., Dubyak, George R., Gurkan, Umut A., Nieman, Marvin T., Sen Gupta, Anirban, Renné, Thomas, Schmaier, Alvin H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824869/
https://ncbi.nlm.nih.gov/pubmed/29376892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92880
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