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Mammalian target of rapamycin inhibition attenuates myocardial ischaemia–reperfusion injury in hypertrophic heart

Pathological cardiac hypertrophy aggravated myocardial infarction and is causally related to autophagy dysfunction and increased oxidative stress. Rapamycin is an inhibitor of serine/threonine kinase mammalian target of rapamycin (mTOR) involved in the regulation of autophagy as well as oxidative/ni...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Ma, Lei‐Lei, Ma, Xin, Kong, Fei‐Juan, Guo, Jun‐Jie, Shi, Hong‐Tao, Zhu, Jian‐Bing, Zou, Yun‐Zeng, Ge, Jun‐Bo
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824378/
https://ncbi.nlm.nih.gov/pubmed/29314656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13451
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