Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK

Prompt coronary reperfusion is the gold standard for minimizing injury following acute myocardial infarction. Rapamycin, mammalian target of Rapamycin (mTOR) inhibitor, exerts preconditioning-like cardioprotective effects against ischemia/reperfusion (I/R) injury. We hypothesized that Rapamycin, giv...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Filippone, Scott M., Samidurai, Arun, Roh, Sean K., Cain, Chad K., He, Jun, Salloum, Fadi N., Kukreja, Rakesh C., Das, Anindita
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360974/
https://ncbi.nlm.nih.gov/pubmed/28373901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4619720
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