Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK

Prompt coronary reperfusion is the gold standard for minimizing injury following acute myocardial infarction. Rapamycin, mammalian target of Rapamycin (mTOR) inhibitor, exerts preconditioning-like cardioprotective effects against ischemia/reperfusion (I/R) injury. We hypothesized that Rapamycin, giv...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Filippone, Scott M., Samidurai, Arun, Roh, Sean K., Cain, Chad K., He, Jun, Salloum, Fadi N., Kukreja, Rakesh C., Das, Anindita
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360974/
https://ncbi.nlm.nih.gov/pubmed/28373901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4619720
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