Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK

Prompt coronary reperfusion is the gold standard for minimizing injury following acute myocardial infarction. Rapamycin, mammalian target of Rapamycin (mTOR) inhibitor, exerts preconditioning-like cardioprotective effects against ischemia/reperfusion (I/R) injury. We hypothesized that Rapamycin, giv...

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Bibliografski detalji
Izdano u:Oxid Med Cell Longev
Glavni autori: Filippone, Scott M., Samidurai, Arun, Roh, Sean K., Cain, Chad K., He, Jun, Salloum, Fadi N., Kukreja, Rakesh C., Das, Anindita
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2017
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Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360974/
https://ncbi.nlm.nih.gov/pubmed/28373901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4619720
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