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Mammalian target of rapamycin inhibition attenuates myocardial ischaemia–reperfusion injury in hypertrophic heart

Pathological cardiac hypertrophy aggravated myocardial infarction and is causally related to autophagy dysfunction and increased oxidative stress. Rapamycin is an inhibitor of serine/threonine kinase mammalian target of rapamycin (mTOR) involved in the regulation of autophagy as well as oxidative/ni...

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Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: Ma, Lei‐Lei, Ma, Xin, Kong, Fei‐Juan, Guo, Jun‐Jie, Shi, Hong‐Tao, Zhu, Jian‐Bing, Zou, Yun‐Zeng, Ge, Jun‐Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824378/
https://ncbi.nlm.nih.gov/pubmed/29314656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13451
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