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Mammalian target of rapamycin inhibition attenuates myocardial ischaemia–reperfusion injury in hypertrophic heart

Pathological cardiac hypertrophy aggravated myocardial infarction and is causally related to autophagy dysfunction and increased oxidative stress. Rapamycin is an inhibitor of serine/threonine kinase mammalian target of rapamycin (mTOR) involved in the regulation of autophagy as well as oxidative/ni...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Ma, Lei‐Lei, Ma, Xin, Kong, Fei‐Juan, Guo, Jun‐Jie, Shi, Hong‐Tao, Zhu, Jian‐Bing, Zou, Yun‐Zeng, Ge, Jun‐Bo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824378/
https://ncbi.nlm.nih.gov/pubmed/29314656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13451
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