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The mutational landscape of MYCN, Lin28b and ALK(F1174L) driven murine neuroblastoma mimics human disease

Genetically engineered mouse models have proven to be essential tools for unraveling fundamental aspects of cancer biology and for testing novel therapeutic strategies. To optimally serve these goals, it is essential that the mouse model faithfully recapitulates the human disease. Recently, novel mo...

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Bibliographic Details
Published in:Oncotarget
Main Authors: De Wilde, Bram, Beckers, Anneleen, Lindner, Sven, Kristina, Althoff, De Preter, Katleen, Depuydt, Pauline, Mestdagh, Pieter, Sante, Tom, Lefever, Steve, Hertwig, Falk, Peng, Zhiyu, Shi, Le-Ming, Lee, Sangkyun, Vandermarliere, Elien, Martens, Lennart, Menten, Björn, Schramm, Alexander, Fischer, Matthias, Schulte, Johannes, Vandesompele, Jo, Speleman, Frank
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823580/
https://ncbi.nlm.nih.gov/pubmed/29492199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23614
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