The mutational landscape of MYCN, Lin28b and ALK(F1174L) driven murine neuroblastoma mimics human disease

Genetically engineered mouse models have proven to be essential tools for unraveling fundamental aspects of cancer biology and for testing novel therapeutic strategies. To optimally serve these goals, it is essential that the mouse model faithfully recapitulates the human disease. Recently, novel mo...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: De Wilde, Bram, Beckers, Anneleen, Lindner, Sven, Kristina, Althoff, De Preter, Katleen, Depuydt, Pauline, Mestdagh, Pieter, Sante, Tom, Lefever, Steve, Hertwig, Falk, Peng, Zhiyu, Shi, Le-Ming, Lee, Sangkyun, Vandermarliere, Elien, Martens, Lennart, Menten, Björn, Schramm, Alexander, Fischer, Matthias, Schulte, Johannes, Vandesompele, Jo, Speleman, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823580/
https://ncbi.nlm.nih.gov/pubmed/29492199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23614
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