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The mutational landscape of MYCN, Lin28b and ALK(F1174L) driven murine neuroblastoma mimics human disease

Genetically engineered mouse models have proven to be essential tools for unraveling fundamental aspects of cancer biology and for testing novel therapeutic strategies. To optimally serve these goals, it is essential that the mouse model faithfully recapitulates the human disease. Recently, novel mo...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: De Wilde, Bram, Beckers, Anneleen, Lindner, Sven, Kristina, Althoff, De Preter, Katleen, Depuydt, Pauline, Mestdagh, Pieter, Sante, Tom, Lefever, Steve, Hertwig, Falk, Peng, Zhiyu, Shi, Le-Ming, Lee, Sangkyun, Vandermarliere, Elien, Martens, Lennart, Menten, Björn, Schramm, Alexander, Fischer, Matthias, Schulte, Johannes, Vandesompele, Jo, Speleman, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823580/
https://ncbi.nlm.nih.gov/pubmed/29492199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23614
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