The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

BACKGROUND: Our previous study has demonstrated that hepatocyte nuclear factor 1α (HNF1α) exerts potent therapeutic effects on hepatocellular carcinoma (HCC). However, the molecular mechanisms by which HNF1α reverses HCC malignancy need to be further elucidated. METHODS: lncRNA microarray was perfor...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ding, Chen-Hong, Yin, Chuan, Chen, Shi-Jie, Wen, Liang-Zhi, Ding, Kai, Lei, Shu-Juan, Liu, Jin-Pei, Wang, Jian, Chen, Kai-xian, Jiang, Hua-liang, Zhang, Xin, Luo, Cheng, Xie, Wei-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822613/
https://ncbi.nlm.nih.gov/pubmed/29466992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0813-1
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