The HNF1α-Regulated LncRNA HNF1α-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells

Expression of cytochrome P450s (P450s) is regulated by epigenetic factors, such as DNA methylation, histone modifications, and noncoding RNAs through different mechanisms. Among these factors, long noncoding RNAs (lncRNAs) have been shown to play important roles in the regulation of gene expression;...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Wang, Yiting, Yan, Liang, Liu, Jingyang, Chen, Shitong, Liu, Guangming, Nie, Yali, Wang, Pei, Yang, Weihong, Chen, Liming, Zhong, Xiaobo, Han, Shengna, Zhang, Lirong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367688/
https://ncbi.nlm.nih.gov/pubmed/30602592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.252940
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