The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

BACKGROUND: Our previous study has demonstrated that hepatocyte nuclear factor 1α (HNF1α) exerts potent therapeutic effects on hepatocellular carcinoma (HCC). However, the molecular mechanisms by which HNF1α reverses HCC malignancy need to be further elucidated. METHODS: lncRNA microarray was perfor...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cancer
Main Authors: Ding, Chen-Hong, Yin, Chuan, Chen, Shi-Jie, Wen, Liang-Zhi, Ding, Kai, Lei, Shu-Juan, Liu, Jin-Pei, Wang, Jian, Chen, Kai-xian, Jiang, Hua-liang, Zhang, Xin, Luo, Cheng, Xie, Wei-Fen
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822613/
https://ncbi.nlm.nih.gov/pubmed/29466992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0813-1
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