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Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells()
Graft-versus-host disease (GVHD) is initiated by antigen-presenting cells (APCs) that prime alloreactive donor T cells. In anti-pathogen responses antigen-bearing APCs receive signals though pattern-recognition receptors (PRRs), including TLRs, which induce the expression of costimulatory molecules...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5822434/ https://ncbi.nlm.nih.gov/pubmed/21098219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002965 |
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