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Profound depletion of host conventional dendritic cells, plasmacytoid dendritic cells and B cells does not prevent GVHD induction

The efficacy of alloSCT is limited by graft-versus-host disease (GVHD). Host hematopoietic antigen presenting cells (APCs) are important initiators of GVHD making them logical targets for GVHD prevention. Conventional dendritic cells (cDCs) are key APCs for T cell responses in other models of T cell...

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Detalhes bibliográficos
Main Authors: Li, Hongmei, Demetris, Anthony J., McNiff, Jennifer, Matte-Martone, Catherine, Tan, Hung Sheng, Rothstein, David M., Lakkis, Fadi G., Shlomchik, Warren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324629/
https://ncbi.nlm.nih.gov/pubmed/22422880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102795
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