Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4 effector memory T cells

Graft-vs.-host disease (GVHD) caused by donor T cells attacking recipient tissues is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (alloSCT). Studies have shown that effector memory T cells (T(EM)) do not cause GVHD but are capable of immune fu...

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Bibliographic Details
Main Authors: Anderson, Britt E, Tang, Anita L, Wang, Ying, Froicu, Monica, Rothstein, David, McNiff, Jennifer M, Demetris, Anthony J, Farber, Donna L, Shlomchik, Warren D, Shlomchik, Mark J
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517133/
https://ncbi.nlm.nih.gov/pubmed/21660940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141678
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