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Effector memory CD4(+) T cells mediate graft-versus-leukemia without inducing graft-versus-host disease

Much of the efficacy of allogeneic hematopoietic stem cell transplantation (alloSCT) in curing hematologic malignancies is due to a graft-versus-leukemia (GVL) effect mediated by donor T cells that recognize recipient alloantigens on leukemic cells. Donor T cells are also important for reconstitutin...

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Bibliografiske detaljer
Main Authors: Zheng, Hong, Matte-Martone, Catherine, Li, Hongmei, Anderson, Britt E., Venketesan, Srividhya, Sheng Tan, Hung, Jain, Dhanpat, McNiff, Jennifer, Shlomchik, Warren D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234071/
https://ncbi.nlm.nih.gov/pubmed/18045967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-109678
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