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Effector memory CD4(+) T cells mediate graft-versus-leukemia without inducing graft-versus-host disease
Much of the efficacy of allogeneic hematopoietic stem cell transplantation (alloSCT) in curing hematologic malignancies is due to a graft-versus-leukemia (GVL) effect mediated by donor T cells that recognize recipient alloantigens on leukemic cells. Donor T cells are also important for reconstitutin...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234071/ https://ncbi.nlm.nih.gov/pubmed/18045967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-109678 |
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