Mechanisms of antigen presentation to T cells in murine graft-versus-host disease: cross-presentation and the appearance of cross-presentation

Recipient antigen-presenting cells (APCs) initiate GVHD by directly presenting host minor histocompatibility antigens (miHAs) to donor CD8 cells. However, later after transplantation, host APCs are replaced by donor APCs, and if pathogenic CD8 cells continue to require APC stimulation, then donor AP...

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Detalhes bibliográficos
Main Authors: Wang, Xiaojian, Li, Hongmei, Matte-Martone, Catherine, Cui, Weiguo, Li, Ning, Tan, Hung Sheng, Roopenian, Derry, Shlomchik, Warren D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236124/
https://ncbi.nlm.nih.gov/pubmed/21963602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-358747
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