High-efficiency RNA-based reprogramming of human primary fibroblasts

Induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine; however, their potential clinical application is hampered by the low efficiency of somatic cell reprogramming. Here, we show that the synergistic activity of synthetic modified mRNAs encoding reprogramming factors a...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Kogut, Igor, McCarthy, Sandra M., Pavlova, Maryna, Astling, David P., Chen, Xiaomi, Jakimenko, Ana, Jones, Kenneth L., Getahun, Andrew, Cambier, John C., Pasmooij, Anna M. G., Jonkman, Marcel F., Roop, Dennis R., Bilousova, Ganna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821705/
https://ncbi.nlm.nih.gov/pubmed/29467427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03190-3
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