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Efficient RNA-based reprogramming of disease-associated primary human fibroblasts into induced pluripotent stem cells

Reprogramming a patient’s somatic cells into induced pluripotent stem cells (iPSCs) holds great promise for disease modeling and the development of autologous cellular therapeutics. However, it remains challenging to consistently reprogram primary human cells, as they are frequently aged, diseased,...

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Publicado en:Methods Mol Biol
Main Authors: McGrath, Patrick S., McGarvey, Shennea S., Kogut, Igor, Bilousova, Ganna
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117588/
https://ncbi.nlm.nih.gov/pubmed/31960386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0301-7_17
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