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Efficient RNA-based reprogramming of disease-associated primary human fibroblasts into induced pluripotent stem cells

Reprogramming a patient’s somatic cells into induced pluripotent stem cells (iPSCs) holds great promise for disease modeling and the development of autologous cellular therapeutics. However, it remains challenging to consistently reprogram primary human cells, as they are frequently aged, diseased,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Methods Mol Biol
Egile Nagusiak: McGrath, Patrick S., McGarvey, Shennea S., Kogut, Igor, Bilousova, Ganna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117588/
https://ncbi.nlm.nih.gov/pubmed/31960386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0301-7_17
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