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Efficient RNA-based reprogramming of disease-associated primary human fibroblasts into induced pluripotent stem cells
Reprogramming a patient’s somatic cells into induced pluripotent stem cells (iPSCs) holds great promise for disease modeling and the development of autologous cellular therapeutics. However, it remains challenging to consistently reprogram primary human cells, as they are frequently aged, diseased,...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7117588/ https://ncbi.nlm.nih.gov/pubmed/31960386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0301-7_17 |
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