Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload

AIMS: In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is...

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Veröffentlicht in:PLoS One
Hauptverfasser: Schirmer, Ilona, Bualeong, Tippaporn, Budde, Heidi, Cimiotti, Diana, Appukuttan, Avinash, Klein, Nicole, Steinwascher, Philip, Reusch, Peter, Mügge, Andreas, Meyer, Rainer, Ladilov, Yury, Jaquet, Kornelia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821345/
https://ncbi.nlm.nih.gov/pubmed/29466442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192322
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