Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload

AIMS: In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscle. However, its role in cardiac pathology is...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schirmer, Ilona, Bualeong, Tippaporn, Budde, Heidi, Cimiotti, Diana, Appukuttan, Avinash, Klein, Nicole, Steinwascher, Philip, Reusch, Peter, Mügge, Andreas, Meyer, Rainer, Ladilov, Yury, Jaquet, Kornelia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821345/
https://ncbi.nlm.nih.gov/pubmed/29466442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192322
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