IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation

Mesenchymal stem cells (MSCs) can give rise to both adipocytes and osteoblasts, but the molecular mechanisms underlying MSC fate determination remain poorly understood. IκB kinase β (IKKβ), a central coordinator of inflammation and immune responses through activation of NF-κB, has been implicated as...

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Publicat a:JCI Insight
Autors principals: Sui, Yipeng, Liu, Zun, Park, Se-Hyung, Thatcher, Sean E., Zhu, Beibei, Fernandez, Joseph P., Molina, Henrik, Kern, Philip A., Zhou, Changcheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821193/
https://ncbi.nlm.nih.gov/pubmed/29367460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96660
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