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Targeting IKKβ in adipocyte lineage cells for treatment of obesity and metabolic dysfunctions

IκB kinase β (IKKβ), a central coordinator of inflammation through activation of NF-κB, has been identified as a potential therapeutic target for the treatment of obesity-associated metabolic dysfunctions. In this study, we evaluated an antisense oligonucleotide (ASO) inhibitor of IKKβ and found tha...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Helsley, Robert N., Sui, Yipeng, Park, Se-Hyung, Liu, Zun, Lee, Richard G., Zhu, Beibei, Kern, Philip A., Zhou, Changcheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931966/
https://ncbi.nlm.nih.gov/pubmed/26991836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2358
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