IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation

Mesenchymal stem cells (MSCs) can give rise to both adipocytes and osteoblasts, but the molecular mechanisms underlying MSC fate determination remain poorly understood. IκB kinase β (IKKβ), a central coordinator of inflammation and immune responses through activation of NF-κB, has been implicated as...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sui, Yipeng, Liu, Zun, Park, Se-Hyung, Thatcher, Sean E., Zhu, Beibei, Fernandez, Joseph P., Molina, Henrik, Kern, Philip A., Zhou, Changcheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821193/
https://ncbi.nlm.nih.gov/pubmed/29367460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96660
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