IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation

Mesenchymal stem cells (MSCs) can give rise to both adipocytes and osteoblasts, but the molecular mechanisms underlying MSC fate determination remain poorly understood. IκB kinase β (IKKβ), a central coordinator of inflammation and immune responses through activation of NF-κB, has been implicated as...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Sui, Yipeng, Liu, Zun, Park, Se-Hyung, Thatcher, Sean E., Zhu, Beibei, Fernandez, Joseph P., Molina, Henrik, Kern, Philip A., Zhou, Changcheng
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821193/
https://ncbi.nlm.nih.gov/pubmed/29367460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96660
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