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Reprogramming of pancreatic acinar cells to functional beta-cells by in vivo transduction of a polycistronic construct containing Pdx1, Ngn3, MafA in mice
To generate new beta-cells after birth is a key focus of regenerative medicine that could greatly aid the major health burden of diabetes. Beta-cell regeneration has been described using four different approaches: 1) the development of beta-cells from putative precursor cells of the adult pancreas t...
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| Publicado en: | Curr Protoc Stem Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5821133/ https://ncbi.nlm.nih.gov/pubmed/28152182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpsc.21 |
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