Reprogramming of Various Cell Types to a Beta-Like State by Pdx1, Ngn3 and MafA

The three transcription factors, PDX1, NGN3 and MAFA, are very important in pancreatic development. Overexpression of these three factors can reprogram both pancreatic exocrine cells and SOX9-positive cells of the liver into cells resembling pancreatic beta cells. In this study we investigate whethe...

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Détails bibliographiques
Auteurs principaux: Akinci, Ersin, Banga, Anannya, Tungatt, Katie, Segal, Joanna, Eberhard, Daniel, Dutton, James R., Slack, Jonathan M. W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843737/
https://ncbi.nlm.nih.gov/pubmed/24312421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082424
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