In vivo reprogramming of Sox9(+) cells in the liver to insulin-secreting ducts

In embryonic development, the pancreas and liver share developmental history up to the stage of bud formation. Therefore, we postulated that direct reprogramming of liver to pancreatic cells can occur when suitable transcription factors are overexpressed. Using a polycistronic vector we misexpress P...

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Detaylı Bibliyografya
Asıl Yazarlar: Banga, Anannya, Akinci, Ersin, Greder, Lucas V., Dutton, James R., Slack, Jonathan M. W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458366/
https://ncbi.nlm.nih.gov/pubmed/22949652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201701109
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