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In vivo reprogramming of Sox9(+) cells in the liver to insulin-secreting ducts
In embryonic development, the pancreas and liver share developmental history up to the stage of bud formation. Therefore, we postulated that direct reprogramming of liver to pancreatic cells can occur when suitable transcription factors are overexpressed. Using a polycistronic vector we misexpress P...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458366/ https://ncbi.nlm.nih.gov/pubmed/22949652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201701109 |
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