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In vivo reprogramming of Sox9(+) cells in the liver to insulin-secreting ducts

In embryonic development, the pancreas and liver share developmental history up to the stage of bud formation. Therefore, we postulated that direct reprogramming of liver to pancreatic cells can occur when suitable transcription factors are overexpressed. Using a polycistronic vector we misexpress P...

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Main Authors: Banga, Anannya, Akinci, Ersin, Greder, Lucas V., Dutton, James R., Slack, Jonathan M. W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458366/
https://ncbi.nlm.nih.gov/pubmed/22949652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201701109
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