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Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA

Pdx1 (pancreatic and duodenal homeobox 1), Ngn3 (neurogenin 3) and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A) have been reported to bring about the transdifferentiation of pancreatic exocrine cells to beta (β) cells in vivo. We have investigated the mechanism of this pro...

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書誌詳細
主要な著者: Akinci, Ersin, Banga, Anannya, Greder, Lucas V., Dutton, James R., Slack, Jonathan M. W.
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286861/
https://ncbi.nlm.nih.gov/pubmed/22150363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111678
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