Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA

Pdx1 (pancreatic and duodenal homeobox 1), Ngn3 (neurogenin 3) and MafA (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A) have been reported to bring about the transdifferentiation of pancreatic exocrine cells to beta (β) cells in vivo. We have investigated the mechanism of this pro...

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Hlavní autoři: Akinci, Ersin, Banga, Anannya, Greder, Lucas V., Dutton, James R., Slack, Jonathan M. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286861/
https://ncbi.nlm.nih.gov/pubmed/22150363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111678
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