Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic β-cells

It has been indicated that the combination of pancreatic and duodenal homeobox 1 (Pdx1), MAF bZIP transcription factor A (MafA) and neurogenin 3 (Ngn3) was able to reprogram various cell types towards pancreatic β-like cells (pβLCs). Paired box 4 (Pax4), a transcription factor, has a key role in reg...

Full description

Saved in:
Bibliographic Details
Published in:Exp Ther Med
Main Authors: Zhang, Ting, Wang, Hongwu, Wang, Tianyou, Wei, Chiju, Jiang, Hui, Jiang, Shayi, Yang, Jingwei, Shao, Jingbo, Ma, Lian
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755441/
https://ncbi.nlm.nih.gov/pubmed/31572507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7854
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items