Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway

We have revealed that a novel stress-inducible protein, Sestrin2, declines in the heart with aging. Moreover, there is an interaction between Sestrin2 and energy sensor AMPK in the heart in response to ischemic stress. The objective of this study is to determine whether Sestrin2-AMPK complex modulat...

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Bibliografiset tiedot
Julkaisussa:J Mol Cell Cardiol
Päätekijät: Quan, Nanhu, Wang, Lin, Chen, Xu, Luckett, Chelsea, Cates, Courtney, Rousselle, Thomas, Zheng, Yang, Li, Ji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820139/
https://ncbi.nlm.nih.gov/pubmed/29325933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.01.005
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