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Metformin-induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

The proliferation and migration of vascular smooth muscle cells are significant in the development and progression of atherosclerosis and plaque rupture. Metformin is a widely used antidiabetic drug, which has been reported to inhibit cell growth and migration. The antiproliferative and antimigrator...

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Bibliografski detalji
Izdano u:Int J Mol Med
Glavni autori: Hao, Biao, Xiao, Yan, Song, Fang, Long, Xiangshu, Huang, Jing, Tian, Maobo, Deng, Shiyan, Wu, Qiang
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819901/
https://ncbi.nlm.nih.gov/pubmed/29286156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3346
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