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Metformin-induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

The proliferation and migration of vascular smooth muscle cells are significant in the development and progression of atherosclerosis and plaque rupture. Metformin is a widely used antidiabetic drug, which has been reported to inhibit cell growth and migration. The antiproliferative and antimigrator...

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書目詳細資料
發表在:Int J Mol Med
Main Authors: Hao, Biao, Xiao, Yan, Song, Fang, Long, Xiangshu, Huang, Jing, Tian, Maobo, Deng, Shiyan, Wu, Qiang
格式: Artigo
語言:Inglês
出版: D.A. Spandidos 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819901/
https://ncbi.nlm.nih.gov/pubmed/29286156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3346
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