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Metformin inhibits high glucose-induced smooth muscle cell proliferation and migration

We investigated the protective effects and mechanism of action of metformin on high glucose-induced smooth muscle cell proliferation and migration. Vascular smooth muscle cells (VSMCs) were subjected to a series of concentrations (0-10 mM) of metformin. CCK-8, wound healing, and transwell assays wer...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhou, Dong-Ming, Ran, Feng, Ni, Hai-Zhen, Sun, Li-Li, Xiao, Lun, Li, Xiao-Qiang, Li, Wen-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138554/
https://ncbi.nlm.nih.gov/pubmed/32208365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102955
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