Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes

A substantial proportion of influenza-related childhood deaths are due to infection with influenza B viruses, which co-circulate in the human population as two antigenically distinct lineages defined by the immunodominant receptor binding protein, hemagglutinin. While broadly cross-reactive, protect...

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Udgivet i:Nat Microbiol
Main Authors: Wohlbold, Teddy John, Podolsky, Kira A., Chromikova, Veronika, Kirkpatrick, Ericka, Falconieri, Veronica, Meade, Philip, Amanat, Fatima, Tan, Jessica, tenOever, Benjamin R., Tan, Gene S., Subramaniam, Sriram, Palese, Peter, Krammer, Florian
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819343/
https://ncbi.nlm.nih.gov/pubmed/28827718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0011-8
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