Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate

Influenza viruses expressing chimeric hemagglutinins (HAs) are important tools in the quest for a universal vaccine. Using cryo-electron tomography, we have determined the structures of a chimeric HA variant that comprises an H1 stalk and an H5 globular head domain (cH5/1 HA) in native and antibody-...

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Bibliografske podrobnosti
izdano v:mBio
Main Authors: Tran, Erin E. H., Podolsky, Kira A., Bartesaghi, Alberto, Kuybeda, Oleg, Grandinetti, Giovanna, Wohlbold, Teddy John, Tan, Gene S., Nachbagauer, Raffael, Palese, Peter, Krammer, Florian, Subramaniam, Sriram
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807363/
https://ncbi.nlm.nih.gov/pubmed/27006464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00257-16
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