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Water-Soluble Palladium Reagents for Cysteine S-Arylation under Ambient Aqueous Conditions
We report the use of a sulfonated biarylphosphine ligand (sSPhos) to promote the chemoselective modification of cysteine containing proteins and peptides with palladium reagents in aqueous medium. The use of sSPhos allowed for the isolation of several air-stable and water-soluble mono- and bis-palla...
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| Publié dans: | Org Lett |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818991/ https://ncbi.nlm.nih.gov/pubmed/28777001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01911 |
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