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Water-Soluble Palladium Reagents for Cysteine S-Arylation under Ambient Aqueous Conditions

We report the use of a sulfonated biarylphosphine ligand (sSPhos) to promote the chemoselective modification of cysteine containing proteins and peptides with palladium reagents in aqueous medium. The use of sSPhos allowed for the isolation of several air-stable and water-soluble mono- and bis-palla...

詳細記述

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書誌詳細
出版年:Org Lett
主要な著者: Rojas, Anthony J., Pentelute, Bradley L., Buchwald, Stephen L.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818991/
https://ncbi.nlm.nih.gov/pubmed/28777001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01911
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