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Computational predictions of cysteine cathepsin‐mediated fibrinogen proteolysis

Fibrin clot formation is a proteolytic cascade of events with thrombin and plasmin identified as the main proteases cleaving fibrinogen precursor, and the fibrin polymer, respectively. Other proteases may be involved directly in fibrin(ogen) cleavage, clot formation, and resolution, or in the degrad...

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Publicat a:Protein Sci
Autors principals: Ferrall‐Fairbanks, Meghan C., West, Dayne M., Douglas, Simone A., Averett, Rodney D., Platt, Manu O.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818743/
https://ncbi.nlm.nih.gov/pubmed/29266558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3366
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