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Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks

Enzymes are catalysts in biochemical reactions that, by definition, increase rates of reactions without being altered or destroyed. However, when that enzyme is a protease, a subclass of enzymes that hydrolyze other proteins, and that protease is in a multiprotease system, protease-as-substrate dyna...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ferrall-Fairbanks, Meghan C., Kieslich, Chris A., Platt, Manu O.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022172/
https://ncbi.nlm.nih.gov/pubmed/31980525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912207117
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