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PACMANS: A bioinformatically informed algorithm to predict, design, and disrupt protease‐on‐protease hydrolysis
Multiple proteases in a system hydrolyze target substrates, but recent evidence indicates that some proteases will degrade other proteases as well. Cathepsin S hydrolysis of cathepsin K is one such example. These interactions may be uni‐ or bi‐directional and change the expected kinetics. To explore...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368069/ https://ncbi.nlm.nih.gov/pubmed/28078782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3113 |
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