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Cathepsin S Cannibalism of Cathepsin K as a Mechanism to Reduce Type I Collagen Degradation

Cathepsins S and K are potent mammalian proteases secreted into the extracellular space and have been implicated in elastin and collagen degradation in diseases such as atherosclerosis and osteoporosis. Studies of individual cathepsins hydrolyzing elastin or collagen have provided insight into their...

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Hlavní autoři: Barry, Zachary T., Platt, Manu O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431690/
https://ncbi.nlm.nih.gov/pubmed/22730330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332684
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