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Cathepsin S Cannibalism of Cathepsin K as a Mechanism to Reduce Type I Collagen Degradation

Cathepsins S and K are potent mammalian proteases secreted into the extracellular space and have been implicated in elastin and collagen degradation in diseases such as atherosclerosis and osteoporosis. Studies of individual cathepsins hydrolyzing elastin or collagen have provided insight into their...

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Autori principali: Barry, Zachary T., Platt, Manu O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431690/
https://ncbi.nlm.nih.gov/pubmed/22730330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332684
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