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Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche

Throughout the process of vascular growth and remodeling, the extracellular matrix (ECM) concurrently undergoes significant changes due to proteolytic activity—regulated by both endothelial and surrounding stromal cells. The role of matrix metalloproteinases has been well-studied in the context of v...

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Detalhes bibliográficos
Publicado no:APL Bioeng
Main Authors: Douglas, Simone A., Haase, Kristina, Kamm, Roger D., Platt, Manu O.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644274/
https://ncbi.nlm.nih.gov/pubmed/33195960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/5.0023342
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