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5-Hydroxymethylcytosine (5hmC) and Ten-eleven translocation 1–3 (TET1–3) proteins in the dorsal root ganglia of mouse: Expression and dynamic regulation in neuropathic pain

Epigenetic mechanisms are increasingly implicated in chronic pain pathology. In this study, we demonstrate that the novel epigenetic mark 5-hydroxymethylcytosine (5hmC) is present in dorsal root ganglia (DRG) neurons and glia, and its levels increase following nerve injury. Furthermore, we show that...

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Detalhes bibliográficos
Publicado no:Somatosens Mot Res
Main Authors: Chamessian, Alexander G., Qadri, Yawar J., Cummins, Matthew, Hendrickson, Michele, Berta, Temugin, Buchheit, Thomas, Van de Ven, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818713/
https://ncbi.nlm.nih.gov/pubmed/28276837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08990220.2017.1292237
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