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Gα12 overexpression induced by miR16 dysregulation contributes to liver fibrosis by promoting autophagy in hepatic stellate cells
BACKGROUND & AIMS: Hepatic stellate cells (HSCs) play a role in liver fibrosis. Guanine nucleotide-binding α-subunit12 (Gα(12)) converges signals from G protein-coupled receptors whose ligand levels are elevated in the environment during liver fibrosis; however, information is lacking on the eff...
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| Pubblicato in: | J Hepatol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818314/ https://ncbi.nlm.nih.gov/pubmed/29080810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2017.10.011 |
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