Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells

Hepatic stellate cells (HSCs) are essential for liver fibrosis. E6 associated protein (E6AP) is one of the E3-ubiquitin-protein ligase and has been studied in proliferation and cellular stress. Currently, no information is available on the role of E6AP on transforming growth factor-β (TGF-β) signali...

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Publicado no:Sci Rep
Main Authors: Kim, Ji Young, Kim, Kyu Min, Yang, Ji Hye, Cho, Sam Seok, Kim, Seung Jung, Park, Su Jung, Ahn, Sang‐Gun, Lee, Gum Hwa, Yang, Jin Won, Lim, Sung Chul, Kang, Keon Wook, Ki, Sung Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965100/
https://ncbi.nlm.nih.gov/pubmed/31949242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57322-w
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