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Recruitment and allosteric stimulation of a histone-deubiquitinating enzyme during heterochromatin assembly
Heterochromatin formation in budding yeast is regulated by the silent information regulator (SIR) complex. The SIR complex comprises the NAD-dependent deacetylase Sir2, the scaffolding protein Sir4, and the nucleosome-binding protein Sir3. Transcriptionally active regions present a challenge to SIR...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818202/ https://ncbi.nlm.nih.gov/pubmed/29288197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000498 |
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