A carregar...
The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms
Aggregation of huntingtin protein arising from expanded polyglutamine (polyQ) sequences in the exon-1 region of mutant huntingtin plays a central role in the pathogenesis of Huntington's disease. The huntingtin aggregation pathways are of therapeutic and diagnostic interest, but obtaining criti...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818184/ https://ncbi.nlm.nih.gov/pubmed/29282287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813667 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|