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Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier
Vascular endothelial growth factor (VEGF), a key angiogenic and permeability factor, plays an important role in new blood vessel formation. However, abnormal VEGF-induced VEGFR2 signaling leads to hyperpermeability. We have shown previously that Rap1, best known for promoting cell adhesion and vesse...
Guardat en:
| Publicat a: | J Cell Sci |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818062/ https://ncbi.nlm.nih.gov/pubmed/29222111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207605 |
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